Edwards, a former UFC champion himself, lost his title to Muhammad last July however the UFC wished to maintain the Birmingham fighter on the London card.
The 33-year-old is anticipated to be granted an opportunity to reclaim his title if he wins his subsequent few battle.
American Muhammad upset the percentages to beat Edwards in Manchester and defends for the primary time.
The 36-year-old is on a 10-fight unbeaten streak, together with one no-contest, and mentioned Della Maddalena was stepping out of the “kiddie pool into the deep finish of the ocean”.
Della Maddalena has received his final 17 fights, seven of these within the UFC, and this will likely be his first time difficult for a UFC title.
“I’m the most effective striker within the welterweight division,” mentioned Muhammad. “I’m the most effective grappler, I’m the most effective wrestler, I’m the most effective fighter.
“We have seen it. Leon Edwards – he was the following one up. He knocked out Kamaru Usman and I made it look simple. I’m going to make it look simple on 10 Might. Individuals maintain doubting me and I’m simply going to maintain breaking these boundaries.”
