Captain Rachel Malcolm misses out with a concussion as Scotland make two adjustments for his or her Six Nations journey to England on Saturday.
Malcolm suffered a head knock within the 25-17 house defeat by Italy final weekend, as did scrum-half Leia Brebner-Holden.
Fly-half Helen Nelson will lead the crew in Malcolm’s absence.
Caity Mattinson takes over at quantity 9 and Jade Konkel is available in at quantity eight as Evie Gallagher strikes to blindside flanker instead of Malcolm.
Rachel McLachlan joins these two within the again row and can earn her fiftieth cap, whereas lock Becky Boyd stays within the crew after making her first begin in opposition to the Italians.
There are a trio of uncapped gamers on the bench, with Gemma Bell among the many ahead choices, whereas Rhea Clarke gives scrum-half cowl and centre Rachel Philipps might additionally make a possible debut.
Scotland opened with victory over Wales however are actually fifth within the desk after defeats by France and Italy.
England, aiming for a seventh successive title, paved the way with three bonus-point wins.
England have received all 23 Six Nations conferences with Scotland, the previous 5 encounters settled by an combination rating of 266-22.
“England have the flexibility to undergo you bodily, in addition they have the flexibility to go spherical you,” mentioned head coach Bryan Easson. “They’ll suffocate you defensively.
“They’ve such a great crew, one to fifteen, or ought to I say one to 40. It doesn’t matter what adjustments they make, they’ve world class gamers coming in.
“It is an enormous process however one we’re definitely up for.
“We have been actually disillusioned with our efficiency in opposition to Italy so this is a chance to place that to mattress and for this group to indicate the progress we have now made.”