Skilled backs Josh Adams and Liam Williams are in however veteran again row Taulupe Faletau is just not within the squad.
Evan Lloyd and Henry Thomas earn their first begins within the entrance row, whereas Dafydd Jenkins, the 2024 Six Nations captain, is at lock. Ben Thomas is chosen forward of Dan Edwards at fly-half, with the latter set to win his first cap from the bench.
Tom Rogers, Freddie Thomas and Blair Murray are set to make their Six Nations bows.
Wales line-up: 15-Williams; 14-Rogers, 13-Watkin, 12-Tompkins, 11-Adams; 10-B. Thomas, 9-T. Williams; 1-G. Thomas, 2-Lloyd, 3-H. Thomas, 4-Rowlands, 5-Jenkins, 6-Botham, 7-Morgan (capt), 8-Wainwright.
Replacements: 16-Dee, 17-Smith, 18-Assiratti, 19-F. Thomas, 20-Reffell, 21-R. Williams, 22-Edwards, 23-Murray.
